KMID : 0869220160200020096
|
|
Journal of Korean Geriatric Psychiatry 2016 Volume.20 No. 2 p.96 ~ p.101
|
|
Impact of Metabolic Syndrome on the White Matter Integrity in Alzheimer¡¯s Disease Patients : Tract-Based Spatial Statistics Study under 3-Tesla MRI
|
|
Suh Hwa-Gyu
Lee Kang-Yoon Lee Young-Min Park Je-Min Lee Byung-Dae Moon Eun-Soo Jeong Hee-Jeong Chung Young-In Kim Tae-Hyung Kim Young-Hoon
|
|
Abstract
|
|
|
Objective£ºThe aim of this study is to determine whether there is any difference in white matter (WM) integrity between Alzheimer¡¯s disease (AD) with metabolic syndrome (MetS) and without MetS.
Methods£ºAltogether, 30 subjects were finally recruited from the Memory Impairment Clinics of Pusan National University Hospital in Korea. All subjects (AD with MetS : n=15, matched AD without MetS for age, gender and year of education : n=15) were underwent 3-tesla magnetic resonance imaging scans of diffusion tensor imaging.
Results£ºThe mean fractional anisotropy of the AD with MetS was lower (p£¼0.05) in right posterior corona radiate, right corticospinal tract and right superior longitudinal fasciculus than that of the AD without MetS.
Conclusion£ºOur findings suggest that WM integrity damage.
|
|
KEYWORD
|
|
Alzheimer¡¯s disease, Metabolic syndrome, White matter integrity, Diffusion tensor imaging
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|